Head tilt - neurological disorder after Fluralaner (Bravecto) in dogs

186 reports to the FDA describe head tilt - neurological disorder in dogs given Fluralaner. That is 0.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

186Reports
89%Marked serious
21%Recovered
17%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
24 23%
1–2 days
22 21%
3–7 days
11 11%
1–4 weeks
20 19%
Over a month
26 25%

How the animals did

Recovered
31 17%
Recovered with lasting effects
8 4.3%
Still unwell when reported
91 49%
Died
1 0.5%
Euthanised
30 16%
Not known
25 13%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
18
4–7 years
53
8–11 years
56
12+ years
52

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause head tilt - neurological disorder in dogs?
186 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Head tilt - neurological disorder with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with head tilt - neurological disorder