Lymphopenia after Famotidine in dogs

78 reports to the FDA describe lymphopenia in dogs given Famotidine. That is 3.0% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

78Reports
81%Marked serious
10%Recovered
44%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
19 29%
1–2 days
9 14%
3–7 days
9 14%
1–4 weeks
15 23%
Over a month
14 21%

How the animals did

Recovered
7 9.0%
Recovered with lasting effects
1 1.3%
Still unwell when reported
24 31%
Died
10 13%
Euthanised
24 31%
Not known
12 15%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
8
4–7 years
27
8–11 years
29
12+ years
10

About this medicine

Type: medicine.

Questions owners ask

Can Famotidine cause lymphopenia in dogs?
78 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lymphopenia with similar medicines

All reported side effects of Famotidine in dogs · Medicines most reported with lymphopenia