Restlessness or agitation after Doxycycline in dogs

67 reports to the FDA describe restlessness or agitation in dogs given Doxycycline. That is 1.7% of all reports for this medicine, compared with 1.6% across reports for all dog medicines.

67Reports
60%Marked serious
27%Recovered
18%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
16 30%
1–2 days
6 11%
3–7 days
5 9.4%
1–4 weeks
7 13%
Over a month
19 36%

How the animals did

Recovered
18 27%
Still unwell when reported
25 37%
Died
5 7.5%
Euthanised
7 10%
Not known
12 18%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
25
4–7 years
18
8–11 years
12
12+ years
9

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause restlessness or agitation in dogs?
67 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

All reported side effects of Doxycycline in dogs · Medicines most reported with restlessness or agitation