General illness after Doxycycline in dogs

24 reports to the FDA describe general illness in dogs given Doxycycline. That is 0.6% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports

88%Marked serious

8.3%Recovered

63%Died or euthanised

14 daysTypical onset

How soon it started

Same day

3 13%

1–2 days

3 13%

3–7 days

2 8.7%

1–4 weeks

4 17%

Over a month

11 48%

How the animals did

Recovered

2 8.3%

Still unwell when reported

7 29%

Died

10 42%

Euthanised

5 21%

Problems reported at the same time

15 63%

15 63%

8 33%

8 33%

8 33%

7 29%

7 29%

6 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause general illness in dogs?: 24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

General illness with similar medicines

General illness after Amoxicillin + Clavulanate (Clavamox) 21 reports · 0.4% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with general illness