Disorientation after Doxycycline in dogs

60 reports to the FDA describe disorientation in dogs given Doxycycline. That is 1.5% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

60Reports

67%Marked serious

22%Recovered

28%Died or euthanised

12 daysTypical onset

How soon it started

Same day

11 21%

1–2 days

4 7.5%

3–7 days

7 13%

1–4 weeks

18 34%

Over a month

13 25%

How the animals did

Recovered

13 22%

Still unwell when reported

22 37%

Died

9 15%

Euthanised

8 13%

Not known

8 13%

Problems reported at the same time

29 48%

25 42%

22 37%

20 33%

18 30%

17 28%

15 25%

15 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause disorientation in dogs?: 60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 12 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Disorientation with similar medicines

Disorientation after Amoxicillin + Clavulanate (Clavamox) 111 reports · 2.1% of its reports
Disorientation after Cefovecin (Convenia) 70 reports · 1.8% of its reports
Disorientation after Enrofloxacin (Baytril) 70 reports · 1.9% of its reports
Disorientation after Metronidazole 55 reports · 1.8% of its reports
Disorientation after Amoxicillin 33 reports · 2.4% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with disorientation