Hypokalaemia after Desoxycorticosterone Pivalate in dogs

The FDA has received 148 reports of hypokalaemia in dogs after Desoxycorticosterone Pivalate. That is 4.4% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

148Reports
61%Marked serious
10%Recovered
9.5%Died or euthanised
26 daysTypical onset
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How soon it started

Same day
10 11%
1–2 days
7 7.4%
3–7 days
8 8.5%
1–4 weeks
27 29%
Over a month
42 45%

How the animals did

Recovered
15 10%
Still unwell when reported
33 22%
Died
4 2.7%
Euthanised
10 6.8%
Not known
86 58%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
33
4–7 years
51
8–11 years
42
12+ years
16

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause hypokalaemia in dogs?
148 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 26 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypokalaemia with similar medicines

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with hypokalaemia