Hyperchloraemia after Desoxycorticosterone Pivalate in dogs

The FDA has received 20 reports of hyperchloraemia in dogs after Desoxycorticosterone Pivalate. That is 0.6% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

20Reports

35%Marked serious

5.0%Recovered

20%Died or euthanised

–Typical onset

How the animals did

Recovered

1 5.0%

Still unwell when reported

1 5.0%

Died

3 15%

Euthanised

1 5.0%

Not known

14 70%

Problems reported at the same time

Hypernatremia

12 60%

Excessive urination

7 35%

High sodium-potassium ratio (na:k ratio)

7 35%

5 25%

5 25%

5 25%

4 20%

4 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause hyperchloraemia in dogs?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with hyperchloraemia