Elevated amylase after Deracoxib (Deramaxx) in dogs

330 reports to the FDA describe elevated amylase in dogs given Deracoxib. That is 3.0% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

330Reports
10%Marked serious
0.9%Recovered
41%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
2 13%
1–2 days
2 13%
3–7 days
5 33%
1–4 weeks
3 20%
Over a month
3 20%

How the animals did

Recovered
1 0.3%
Recovered with lasting effects
2 0.6%
Still unwell when reported
11 3.3%
Died
124 38%
Euthanised
10 3.0%
Not known
182 55%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
29
4–7 years
73
8–11 years
139
12+ years
86

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause elevated amylase in dogs?
330 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated amylase with similar medicines

All reported side effects of Deracoxib in dogs · Medicines most reported with elevated amylase