Reddening of the skin after Cyclosporine (Atopica) in dogs

The FDA has received 58 reports of reddening of the skin in dogs after Cyclosporine. That is 0.4% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

58Reports

62%Marked serious

34%Recovered

10%Died or euthanised

14 daysTypical onset

How soon it started

Same day

11 31%

1–2 days

3 8.6%

3–7 days

0 0.0%

1–4 weeks

9 26%

Over a month

12 34%

How the animals did

Recovered

19 33%

Recovered with lasting effects

1 1.7%

Still unwell when reported

23 40%

Died

2 3.4%

Euthanised

4 6.9%

Not known

9 16%

Problems reported at the same time

27 47%

12 21%

12 21%

9 16%

9 16%

8 14%

8 14%

7 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause reddening of the skin in dogs?: 58 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Reddening of the skin with similar medicines

Reddening of the skin after Oclacitinib (Apoquel) 246 reports · 0.8% of its reports
Reddening of the skin after Ilunocitinib (Zenrelia) 24 reports · 1.1% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with reddening of the skin