Behaviour change after Chondroitin + Glucosamine in dogs

146 reports to the FDA describe behaviour change in dogs given Chondroitin + Glucosamine. That is 5.6% of all reports for this medicine, compared with 2.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

146Reports

55%Marked serious

32%Recovered

19%Died or euthanised

31 daysTypical onset

How soon it started

Same day

20 20%

1–2 days

9 9.2%

3–7 days

10 10%

1–4 weeks

10 10%

Over a month

49 50%

How the animals did

Recovered

41 28%

Recovered with lasting effects

6 4.1%

Still unwell when reported

40 27%

Died

15 10%

Euthanised

13 8.9%

Not known

31 21%

Problems reported at the same time

43 29%

42 29%

34 23%

28 19%

27 18%

23 16%

19 13%

Restlessness or agitation

18 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Chondroitin + Glucosamine cause behaviour change in dogs?: 146 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 31 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

Behaviour change after Melarsomine (Immiticide) 278 reports · 1.2% of its reports
Behaviour change after Polysulfated Glycosaminoglycan 178 reports · 3.3% of its reports
Behaviour change after Diphenhydramine 251 reports · 5.3% of its reports
Behaviour change after Butorphanol 151 reports · 3.4% of its reports
Behaviour change after Cefpodoxime 162 reports · 4.0% of its reports
Behaviour change after Tramadol 192 reports · 5.1% of its reports
Behaviour change after Florfenicol + Mometasone + Terbinafine 339 reports · 9.6% of its reports
Behaviour change after Desoxycorticosterone Pivalate 174 reports · 5.2% of its reports
Behaviour change after Propofol 71 reports · 2.3% of its reports
Behaviour change after Dirlotapide 107 reports · 3.8% of its reports

All reported side effects of Chondroitin + Glucosamine in dogs · Medicines most reported with behaviour change