Liver problems after Cefovecin (Convenia) in dogs

The FDA has received 403 reports of liver problems in dogs after Cefovecin. That is 11% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

403Reports
55%Marked serious
3.5%Recovered
34%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
57 19%
1–2 days
65 22%
3–7 days
60 20%
1–4 weeks
69 23%
Over a month
51 17%

How the animals did

Recovered
13 3.2%
Recovered with lasting effects
1 0.2%
Still unwell when reported
176 44%
Died
69 17%
Euthanised
70 17%
Not known
74 18%

Problems reported at the same time

Age of the animals

Under 1 year
17
1–3 years
33
4–7 years
132
8–11 years
117
12+ years
99

About this medicine

Cefovecin a long-acting antibiotic injection.

Products with this ingredient include Convenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cefovecin cause liver problems in dogs?
403 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Cefovecin in dogs · Medicines most reported with liver problems