Increased heart rate after Butorphanol in dogs

The FDA has received 22 reports of increased heart rate in dogs after Butorphanol. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

22Reports

100%Marked serious

32%Recovered

23%Died or euthanised

1 daysTypical onset

How soon it started

Same day

8 44%

1–2 days

2 11%

3–7 days

3 17%

1–4 weeks

2 11%

Over a month

3 17%

How the animals did

Recovered

7 32%

Still unwell when reported

6 27%

Died

1 4.5%

Euthanised

4 18%

Not known

4 18%

Problems reported at the same time

10 45%

9 41%

8 36%

8 36%

6 27%

6 27%

5 23%

5 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Butorphanol cause increased heart rate in dogs?: 22 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Increased heart rate with similar medicines

Increased heart rate after Melarsomine (Immiticide) 28 reports · 0.1% of its reports
Increased heart rate after Polysulfated Glycosaminoglycan 25 reports · 0.5% of its reports
Increased heart rate after Diphenhydramine 43 reports · 0.9% of its reports
Increased heart rate after Tramadol 20 reports · 0.5% of its reports
Increased heart rate after Famotidine 20 reports · 0.8% of its reports

All reported side effects of Butorphanol in dogs · Medicines most reported with increased heart rate