Excessive thirst after Buprenorphine in dogs

25 reports to the FDA describe excessive thirst in dogs given Buprenorphine. That is 1.6% of all reports for this medicine, compared with 1.4% across reports for all dog medicines.

25Reports
80%Marked serious
0.0%Recovered
20%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
9 45%
1–2 days
0 0.0%
3–7 days
6 30%
1–4 weeks
3 15%
Over a month
2 10%

How the animals did

Still unwell when reported
17 68%
Died
1 4.0%
Euthanised
4 16%
Not known
3 12%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
3
4–7 years
5
8–11 years
9
12+ years
7

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause excessive thirst in dogs?
25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

All reported side effects of Buprenorphine in dogs · Medicines most reported with excessive thirst