Spinosad (Comfortis) side effects in Mastiffs

234 FDA reports involve Spinosad in a Mastiff. These are the problems they describe.

Vomiting
157 67%
Didn't stop fleas
40 17%
Lethargy
19 8.1%
Itching
13 5.6%
Seizures
9 3.8%
Death
9 3.8%
Loss of appetite
8 3.4%
Underdose
7 3.0%
Wobbliness (ataxia)
7 3.0%
Drug dose omission
5 2.1%
Diarrhea
5 2.1%
Overdose
4 1.7%

All reports for Spinosad in dogs