Increased percentage reticulocytes after Bordetella Vaccine in dogs

The FDA has received 54 reports of increased percentage reticulocytes in dogs after Bordetella Vaccine. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

54Reports
81%Marked serious
11%Recovered
22%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
7 16%
1–2 days
4 9.3%
3–7 days
11 26%
1–4 weeks
13 30%
Over a month
8 19%

How the animals did

Recovered
4 7.4%
Recovered with lasting effects
2 3.7%
Still unwell when reported
24 44%
Died
5 9.3%
Euthanised
7 13%
Not known
12 22%

Problems reported at the same time

Blood problems
30 56%
Lethargy
27 50%
Leucocytosis
27 50%
Neutrophilia
27 50%
Liver problems
26 48%
Loss of appetite
24 44%
Vomiting
24 44%
Monocytosis
20 37%

Age of the animals

Under 1 year
3
1–3 years
8
4–7 years
25
8–11 years
12
12+ years
5

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause increased percentage reticulocytes in dogs?
54 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Increased percentage reticulocytes with similar medicines

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with increased percentage reticulocytes