Increased percentage reticulocytes after Rabies Vaccine in dogs

The FDA has received 63 reports of increased percentage reticulocytes in dogs after Rabies Vaccine. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

63Reports
84%Marked serious
13%Recovered
25%Died or euthanised
21 daysTypical onset
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How soon it started

Same day
3 6.5%
1–2 days
5 11%
3–7 days
8 17%
1–4 weeks
13 28%
Over a month
17 37%

How the animals did

Recovered
6 9.5%
Recovered with lasting effects
2 3.2%
Still unwell when reported
24 38%
Died
9 14%
Euthanised
7 11%
Not known
15 24%

Problems reported at the same time

Blood problems
35 56%
Lethargy
34 54%
Liver problems
33 52%
Leucocytosis
28 44%
Vomiting
27 43%
Neutrophilia
25 40%
Loss of appetite
25 40%
Kidney problems
22 35%

Age of the animals

Under 1 year
5
1–3 years
11
4–7 years
24
8–11 years
13
12+ years
8

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Rabies Vaccine cause increased percentage reticulocytes in dogs?
63 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 21 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Increased percentage reticulocytes with similar medicines

All reported side effects of Rabies Vaccine in dogs · Medicines most reported with increased percentage reticulocytes