Monocytosis after Bordetella Vaccine in dogs

135 reports to the FDA describe monocytosis in dogs given Bordetella Vaccine. That is 1.4% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

135Reports

83%Marked serious

12%Recovered

35%Died or euthanised

5 daysTypical onset

How soon it started

Same day

23 20%

1–2 days

24 21%

3–7 days

18 16%

1–4 weeks

30 26%

Over a month

21 18%

How the animals did

Recovered

15 11%

Recovered with lasting effects

1 0.7%

Still unwell when reported

58 43%

Died

12 8.9%

Euthanised

35 26%

Not known

14 10%

Problems reported at the same time

90 67%

80 59%

72 53%

67 50%

66 49%

65 48%

60 44%

47 35%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause monocytosis in dogs?: 135 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Monocytosis with similar medicines

Monocytosis after Rabies Vaccine 158 reports · 1.6% of its reports
Monocytosis after Leptospirosis Vaccine 149 reports · 1.9% of its reports
Monocytosis after Lyme Vaccine 35 reports · 0.5% of its reports
Monocytosis after Distemper-parvo Vaccine 119 reports · 1.8% of its reports

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with monocytosis