Vestibular disorder after Bedinvetmab (Librela) in dogs

The FDA has received 362 reports of vestibular disorder in dogs after Bedinvetmab. That is 1.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

362Reports

76%Marked serious

12%Recovered

19%Died or euthanised

11 daysTypical onset

How soon it started

Same day

43 14%

1–2 days

44 14%

3–7 days

51 16%

1–4 weeks

100 32%

Over a month

78 25%

How the animals did

Recovered

43 12%

Still unwell when reported

207 57%

Died

12 3.3%

Euthanised

56 15%

Not known

44 12%

Problems reported at the same time

Head tilt - neurological disorder

147 41%

110 30%

108 30%

70 19%

69 19%

68 19%

52 14%

34 9.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

289

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause vestibular disorder in dogs?: 362 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vestibular disorder with similar medicines

Vestibular disorder after Lokivetmab (Cytopoint) 34 reports · 0.5% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with vestibular disorder