Nystagmus after Bedinvetmab (Librela) in dogs

The FDA has received 293 reports of nystagmus in dogs after Bedinvetmab. That is 1.5% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

293Reports

82%Marked serious

13%Recovered

23%Died or euthanised

9 daysTypical onset

How soon it started

Same day

46 19%

1–2 days

41 17%

3–7 days

30 13%

1–4 weeks

57 24%

Over a month

65 27%

How the animals did

Recovered

38 13%

Still unwell when reported

166 57%

Died

15 5.1%

Euthanised

51 17%

Not known

23 7.8%

Problems reported at the same time

Head tilt - neurological disorder

139 47%

117 40%

108 37%

80 27%

73 25%

66 23%

36 12%

34 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

238

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause nystagmus in dogs?: 293 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Nystagmus with similar medicines

Nystagmus after Lokivetmab (Cytopoint) 37 reports · 0.6% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with nystagmus