Underdose after Bedinvetmab (Librela) in dogs

The FDA has received 118 reports of underdose in dogs after Bedinvetmab. That is 0.6% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported less often than average with this medicine.

118Reports

64%Marked serious

10%Recovered

25%Died or euthanised

14 daysTypical onset

How soon it started

Same day

20 21%

1–2 days

13 14%

3–7 days

6 6.3%

1–4 weeks

23 24%

Over a month

33 35%

How the animals did

Recovered

11 9.3%

Recovered with lasting effects

1 0.8%

Still unwell when reported

63 53%

Died

12 10%

Euthanised

18 15%

Not known

13 11%

Problems reported at the same time

Death

30 25%

Didn't work as expected

28 24%

22 19%

19 16%

18 15%

14 12%

13 11%

12 10%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause underdose in dogs?: 118 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Underdose with similar medicines

Underdose after Lokivetmab (Cytopoint) 138 reports · 2.1% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with underdose