Spondylosis after Bedinvetmab (Librela) in dogs

135 reports to the FDA describe spondylosis in dogs given Bedinvetmab. That is 0.7% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

135Reports

94%Marked serious

3.7%Recovered

30%Died or euthanised

14 daysTypical onset

How soon it started

Same day

16 14%

1–2 days

17 15%

3–7 days

18 16%

1–4 weeks

21 18%

Over a month

43 37%

How the animals did

Recovered

4 3.0%

Recovered with lasting effects

1 0.7%

Still unwell when reported

85 63%

Died

12 8.9%

Euthanised

28 21%

Not known

5 3.7%

Problems reported at the same time

Abnormal radiograph finding

55 41%

43 32%

41 30%

40 30%

39 29%

Proprioception deficit

31 23%

Unable to walk

28 21%

Lethargy

25 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause spondylosis in dogs?: 135 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with spondylosis