Splenic neoplasm after Bedinvetmab (Librela) in dogs

111 reports to the FDA describe splenic neoplasm in dogs given Bedinvetmab. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

111Reports

99%Marked serious

3.6%Recovered

50%Died or euthanised

10 daysTypical onset

How soon it started

Same day

23 23%

1–2 days

7 7.1%

3–7 days

14 14%

1–4 weeks

22 22%

Over a month

33 33%

How the animals did

Recovered

4 3.6%

Still unwell when reported

43 39%

Died

16 14%

Euthanised

39 35%

Not known

9 8.1%

Problems reported at the same time

54 49%

51 46%

44 40%

37 33%

25 23%

19 17%

19 17%

17 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause splenic neoplasm in dogs?: 111 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with splenic neoplasm