Paresis after Bedinvetmab (Librela) in dogs

157 reports to the FDA describe paresis in dogs given Bedinvetmab. That is 0.8% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

157Reports

96%Marked serious

7.0%Recovered

33%Died or euthanised

4 daysTypical onset

How soon it started

Same day

30 23%

1–2 days

28 22%

3–7 days

21 16%

1–4 weeks

15 12%

Over a month

35 27%

How the animals did

Recovered

11 7.0%

Still unwell when reported

82 52%

Died

15 9.6%

Euthanised

37 24%

Not known

12 7.6%

Problems reported at the same time

Wobbliness (ataxia)

67 43%

Weakness

53 34%

Death

52 33%

Proprioception deficit

37 24%

37 24%

33 21%

24 15%

20 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause paresis in dogs?: 157 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with paresis