Malaise after Bedinvetmab (Librela) in dogs

The FDA has received 70 reports of malaise in dogs after Bedinvetmab. That is 0.4% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

70Reports

77%Marked serious

13%Recovered

41%Died or euthanised

3 daysTypical onset

How soon it started

Same day

21 34%

1–2 days

8 13%

3–7 days

8 13%

1–4 weeks

7 11%

Over a month

17 28%

How the animals did

Recovered

9 13%

Still unwell when reported

27 39%

Died

7 10%

Euthanised

22 31%

Not known

5 7.1%

Problems reported at the same time

32 46%

29 41%

21 30%

19 27%

13 19%

13 19%

13 19%

12 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause malaise in dogs?: 70 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Malaise with similar medicines

Malaise after Lokivetmab (Cytopoint) 49 reports · 0.8% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with malaise