Low platelet count after Bedinvetmab (Librela) in dogs

The FDA has received 169 reports of low platelet count in dogs after Bedinvetmab. That is 0.9% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

169Reports

99%Marked serious

3.0%Recovered

36%Died or euthanised

15 daysTypical onset

How soon it started

Same day

17 11%

1–2 days

13 8.7%

3–7 days

19 13%

1–4 weeks

50 34%

Over a month

50 34%

How the animals did

Recovered

5 3.0%

Still unwell when reported

92 54%

Died

22 13%

Euthanised

39 23%

Not known

11 6.5%

Problems reported at the same time

78 46%

63 37%

63 37%

61 36%

60 36%

36 21%

35 21%

34 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause low platelet count in dogs?: 169 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 15 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Low platelet count with similar medicines

Low platelet count after Lokivetmab (Cytopoint) 73 reports · 1.1% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with low platelet count