Inappropriate elimination after Bedinvetmab (Librela) in dogs

The FDA has received 97 reports of inappropriate elimination in dogs after Bedinvetmab. That is 0.5% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

97Reports

81%Marked serious

4.1%Recovered

44%Died or euthanised

8 daysTypical onset

How soon it started

Same day

25 27%

1–2 days

9 9.9%

3–7 days

10 11%

1–4 weeks

21 23%

Over a month

26 29%

How the animals did

Recovered

4 4.1%

Still unwell when reported

34 35%

Died

14 14%

Euthanised

29 30%

Not known

16 16%

Problems reported at the same time

43 44%

28 29%

20 21%

19 20%

19 20%

18 19%

16 16%

16 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause inappropriate elimination in dogs?: 97 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with inappropriate elimination