Enlarged lymph node (localised) after Bedinvetmab (Librela) in dogs

The FDA has received 65 reports of enlarged lymph node (localised) in dogs after Bedinvetmab. That is 0.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

65Reports

75%Marked serious

3.1%Recovered

25%Died or euthanised

24 daysTypical onset

How soon it started

Same day

4 7.5%

1–2 days

7 13%

3–7 days

10 19%

1–4 weeks

9 17%

Over a month

23 43%

How the animals did

Recovered

2 3.1%

Still unwell when reported

42 65%

Died

2 3.1%

Euthanised

14 22%

Not known

5 7.7%

Problems reported at the same time

19 29%

18 28%

16 25%

16 25%

13 20%

13 20%

12 18%

Abnormal radiograph finding

12 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause enlarged lymph node (localised) in dogs?: 65 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 24 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Enlarged lymph node (localised) with similar medicines

Enlarged lymph node (localised) after Lokivetmab (Cytopoint) 32 reports · 0.5% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with enlarged lymph node (localised)