Elevated globulins after Bedinvetmab (Librela) in dogs

The FDA has received 212 reports of elevated globulins in dogs after Bedinvetmab. That is 1.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

212Reports

78%Marked serious

4.7%Recovered

25%Died or euthanised

17 daysTypical onset

How soon it started

Same day

17 9.6%

1–2 days

25 14%

3–7 days

25 14%

1–4 weeks

54 31%

Over a month

56 32%

How the animals did

Recovered

9 4.2%

Recovered with lasting effects

1 0.5%

Still unwell when reported

139 66%

Died

19 9.0%

Euthanised

33 16%

Not known

11 5.2%

Problems reported at the same time

95 45%

79 37%

62 29%

57 27%

56 26%

52 25%

49 23%

46 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause elevated globulins in dogs?: 212 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 17 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated globulins with similar medicines

Elevated globulins after Lokivetmab (Cytopoint) 69 reports · 1.1% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with elevated globulins