Elevated gamma-glutamyl transferase (ggt) after Bedinvetmab (Librela) in dogs

72 reports to the FDA describe elevated gamma-glutamyl transferase (ggt) in dogs given Bedinvetmab. That is 0.4% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

72Reports
78%Marked serious
5.6%Recovered
19%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
9 16%
1–2 days
7 13%
3–7 days
6 11%
1–4 weeks
15 27%
Over a month
18 33%

How the animals did

Recovered
3 4.2%
Recovered with lasting effects
1 1.4%
Still unwell when reported
47 65%
Died
1 1.4%
Euthanised
13 18%
Not known
7 9.7%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
3
8–11 years
26
12+ years
42

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause elevated gamma-glutamyl transferase (ggt) in dogs?
72 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated gamma-glutamyl transferase (ggt) with similar medicines

All reported side effects of Bedinvetmab in dogs · Medicines most reported with elevated gamma-glutamyl transferase (ggt)