Dehydration after Bedinvetmab (Librela) in dogs

The FDA has received 191 reports of dehydration in dogs after Bedinvetmab. That is 1.0% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

191Reports

86%Marked serious

6.3%Recovered

38%Died or euthanised

7 daysTypical onset

How soon it started

Same day

33 19%

1–2 days

33 19%

3–7 days

24 14%

1–4 weeks

41 23%

Over a month

44 25%

How the animals did

Recovered

12 6.3%

Still unwell when reported

99 52%

Died

11 5.8%

Euthanised

62 32%

Not known

7 3.7%

Problems reported at the same time

118 62%

103 54%

95 50%

75 39%

73 38%

71 37%

60 31%

47 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

126

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause dehydration in dogs?: 191 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Lokivetmab (Cytopoint) 95 reports · 1.5% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with dehydration