Abnormal posture after Bedinvetmab (Librela) in dogs

The FDA has received 190 reports of abnormal posture in dogs after Bedinvetmab. That is 1.0% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

190Reports

76%Marked serious

7.4%Recovered

26%Died or euthanised

17 daysTypical onset

How soon it started

Same day

31 20%

1–2 days

18 11%

3–7 days

13 8.3%

1–4 weeks

32 20%

Over a month

63 40%

How the animals did

Recovered

14 7.4%

Still unwell when reported

114 60%

Died

5 2.6%

Euthanised

45 24%

Not known

12 6.3%

Problems reported at the same time

62 33%

50 26%

42 22%

35 18%

33 17%

31 16%

Didn't work as expected

26 14%

Liver problems

26 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

104

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause abnormal posture in dogs?: 190 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 17 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with abnormal posture