Behaviour change after Atipamezole in dogs

The FDA has received 76 reports of behaviour change in dogs after Atipamezole. That is 2.9% of all reports for this medicine, compared with 2.5% across reports for all dog medicines.

76Reports
50%Marked serious
24%Recovered
21%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
33 62%
1–2 days
8 15%
3–7 days
2 3.8%
1–4 weeks
1 1.9%
Over a month
9 17%

How the animals did

Recovered
17 22%
Recovered with lasting effects
1 1.3%
Still unwell when reported
22 29%
Died
12 16%
Euthanised
4 5.3%
Not known
20 26%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
17
4–7 years
24
8–11 years
16
12+ years
7

About this medicine

Type: medicine.

Questions owners ask

Can Atipamezole cause behaviour change in dogs?
76 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Atipamezole in dogs · Medicines most reported with behaviour change