Didn't work as expected after Atipamezole in dogs

The FDA has received 830 reports of didn't work as expected in dogs after Atipamezole. That is 31% of all reports for this medicine, compared with 13% across reports for all dog medicines, so it is reported unusually often with this medicine.

830Reports
24%Marked serious
23%Recovered
9.5%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
265 62%
1–2 days
41 9.5%
3–7 days
31 7.2%
1–4 weeks
60 14%
Over a month
33 7.7%

How the animals did

Recovered
184 22%
Recovered with lasting effects
3 0.4%
Still unwell when reported
111 13%
Died
69 8.3%
Euthanised
10 1.2%
Not known
453 55%

Problems reported at the same time

Age of the animals

Under 1 year
55
1–3 years
155
4–7 years
273
8–11 years
179
12+ years
58

About this medicine

Type: medicine.

Questions owners ask

Can Atipamezole cause didn't work as expected in dogs?
830 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

All reported side effects of Atipamezole in dogs · Medicines most reported with didn't work as expected