Apoquel side effects in dogs

87 reports sent to the FDA between 2015 and 2026 involve Apoquel in dogs. The most reported problems were vomiting, lethargy, loss of appetite. 56% were marked serious.

87Reports
56%Marked serious
0.0%Only medicine involved
36%Recovered
6.9%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

25 29%
Lethargy
16 18%
Loss of appetite
15 17%
Diarrhea
10 11%
Breathing problems
8 9.2%
Itching
8 9.2%
Liver problems
7 8.0%
Tremors
7 8.0%
Seizures
6 6.9%
Swelling
5 5.7%
Excessive thirst
5 5.7%
Skin rash or irritation
5 5.7%
Blood problems
4 4.6%
Kidney problems
4 4.6%
Skin redness
4 4.6%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
8 9.2%
Didn't work as expected
2 2.3%
Didn't prevent heartworm
1 1.1%

How soon problems started

Same day
10 24%
1–2 days
2 4.9%
3–7 days
1 2.4%
1–4 weeks
6 15%
Over a month
22 54%

Time from the first dose to the first sign, where both dates were reported (41 reports).

How the animals did

Recovered
28 32%
Recovered with lasting effects
3 3.4%
Still unwell when reported
35 40%
Died
3 3.4%
Euthanised
3 3.4%
Not known
15 17%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other medicines for dogs