Monocytosis after Ampicillin in dogs

78 reports to the FDA describe monocytosis in dogs given Ampicillin. That is 8.0% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

78Reports
82%Marked serious
13%Recovered
46%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
7 12%
1–2 days
9 15%
3–7 days
12 20%
1–4 weeks
18 31%
Over a month
13 22%

How the animals did

Recovered
10 13%
Still unwell when reported
21 27%
Died
13 17%
Euthanised
23 29%
Not known
11 14%

Problems reported at the same time

Age of the animals

Under 1 year
16
1–3 years
9
4–7 years
27
8–11 years
17
12+ years
9

About this medicine

Type: medicine.

Questions owners ask

Can Ampicillin cause monocytosis in dogs?
78 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Monocytosis with similar medicines

All reported side effects of Ampicillin in dogs · Medicines most reported with monocytosis