Weakness after Amoxicillin in dogs

The FDA has received 75 reports of weakness in dogs after Amoxicillin. That is 5.6% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

75Reports

75%Marked serious

9.3%Recovered

43%Died or euthanised

11 daysTypical onset

How soon it started

Same day

12 20%

1–2 days

6 10%

3–7 days

12 20%

1–4 weeks

8 13%

Over a month

22 37%

How the animals did

Recovered

7 9.3%

Still unwell when reported

23 31%

Died

13 17%

Euthanised

19 25%

Not known

13 17%

Problems reported at the same time

37 49%

32 43%

32 43%

31 41%

30 40%

21 28%

17 23%

16 21%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause weakness in dogs?: 75 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weakness with similar medicines

Weakness after Amoxicillin + Clavulanate (Clavamox) 194 reports · 3.6% of its reports
Weakness after Doxycycline 150 reports · 3.7% of its reports
Weakness after Cefovecin (Convenia) 130 reports · 3.4% of its reports
Weakness after Enrofloxacin (Baytril) 215 reports · 5.7% of its reports
Weakness after Metronidazole 176 reports · 5.7% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with weakness