Lameness after Amoxicillin in dogs

The FDA has received 21 reports of lameness in dogs after Amoxicillin. That is 1.6% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports

86%Marked serious

14%Recovered

33%Died or euthanised

12 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

3 19%

3–7 days

3 19%

1–4 weeks

7 44%

Over a month

3 19%

How the animals did

Recovered

3 14%

Still unwell when reported

8 38%

Died

1 4.8%

Euthanised

6 29%

Not known

3 14%

Problems reported at the same time

11 52%

9 43%

7 33%

7 33%

7 33%

5 24%

5 24%

4 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause lameness in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 12 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lameness with similar medicines

Lameness after Amoxicillin + Clavulanate (Clavamox) 132 reports · 2.5% of its reports
Lameness after Doxycycline 109 reports · 2.7% of its reports
Lameness after Cefovecin (Convenia) 53 reports · 1.4% of its reports
Lameness after Enrofloxacin (Baytril) 125 reports · 3.3% of its reports
Lameness after Metronidazole 74 reports · 2.4% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with lameness