Diarrhea after Amitraz + Fipronil + S-methoprene in dogs

The FDA has received 32 reports of diarrhea in dogs after Amitraz + Fipronil + S-methoprene. That is 7.0% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Fipronil kills fleas and ticks (spot-on).

Questions owners ask

Can Amitraz + Fipronil + S-methoprene cause diarrhea in dogs?

32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 35 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

• Diarrhea after Spinosad (Comfortis) 2,388 reports · 4.2% of its reports
• Diarrhea after Lufenuron + Milbemycin Oxime (Sentinel) 2,524 reports · 9.7% of its reports
• Diarrhea after Imidacloprid + Moxidectin (Advantage Multi) 1,203 reports · 9.2% of its reports
• Diarrhea after Nitenpyram (Capstar) 626 reports · 5.8% of its reports
• Diarrhea after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 800 reports · 8.0% of its reports
• Diarrhea after Fipronil + S-methoprene (Frontline Plus) 230 reports · 7.8% of its reports
• Diarrhea after Flumethrin + Imidacloprid (Seresto) 130 reports · 5.7% of its reports
• Diarrhea after Imidacloprid 93 reports · 4.9% of its reports
• Diarrhea after Fipronil 123 reports · 8.7% of its reports
• Diarrhea after Lufenuron 182 reports · 18% of its reports

All reported side effects of Amitraz + Fipronil + S-methoprene in dogs · Medicines most reported with diarrhea