Behaviour change after Amantadine in dogs

22 reports to the FDA describe behaviour change in dogs given Amantadine. That is 4.3% of all reports for this medicine, compared with 2.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

22Reports
64%Marked serious
18%Recovered
32%Died or euthanised
21 daysTypical onset
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How soon it started

Same day
3 14%
1–2 days
4 19%
3–7 days
1 4.8%
1–4 weeks
5 24%
Over a month
8 38%

How the animals did

Recovered
4 18%
Still unwell when reported
7 32%
Died
2 9.1%
Euthanised
5 23%
Not known
4 18%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
1
8–11 years
8
12+ years
11

About this medicine

Type: medicine.

Questions owners ask

Can Amantadine cause behaviour change in dogs?
22 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 21 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Amantadine in dogs · Medicines most reported with behaviour change