Injection site reaction after Acepromazine in dogs

The FDA has received 96 reports of injection site reaction in dogs after Acepromazine. That is 5.5% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

96Reports

47%Marked serious

21%Recovered

6.3%Died or euthanised

2 daysTypical onset

How soon it started

Same day

23 27%

1–2 days

20 24%

3–7 days

15 18%

1–4 weeks

18 21%

Over a month

8 9.5%

How the animals did

Recovered

20 21%

Still unwell when reported

39 41%

Died

2 2.1%

Euthanised

4 4.2%

Not known

31 32%

Problems reported at the same time

Swelling

43 45%

Loss of appetite

13 14%

Lethargy

11 11%

Didn't work as expected

10 10%

Application site reaction

9 9.4%

Diarrhea

8 8.3%

Hair loss

8 8.3%

Pain

8 8.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Acepromazine cause injection site reaction in dogs?: 96 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Melarsomine (Immiticide) 3,290 reports · 15% of its reports
Injection site reaction after Polysulfated Glycosaminoglycan 263 reports · 4.8% of its reports
Injection site reaction after Diphenhydramine 398 reports · 8.4% of its reports
Injection site reaction after Butorphanol 479 reports · 11% of its reports
Injection site reaction after Cefpodoxime 81 reports · 2.0% of its reports
Injection site reaction after Tramadol 123 reports · 3.3% of its reports
Injection site reaction after Desoxycorticosterone Pivalate 165 reports · 4.9% of its reports
Injection site reaction after Propofol 170 reports · 5.5% of its reports
Injection site reaction after Isoflurane 126 reports · 4.6% of its reports
Injection site reaction after Cephalexin 31 reports · 1.2% of its reports

All reported side effects of Acepromazine in dogs · Medicines most reported with injection site reaction