Hyperphosphataemia after Velagliflozin (Senvelgo) in cats

The FDA has received 79 reports of hyperphosphataemia in cats after Velagliflozin. That is 1.6% of all reports for this medicine, compared with 1.0% across reports for all cat medicines, so it is reported unusually often with this medicine.

79Reports
57%Marked serious
0.0%Recovered
34%Died or euthanised
11 daysTypical onset
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How soon it started

Same day
5 6.9%
1–2 days
11 15%
3–7 days
17 24%
1–4 weeks
16 22%
Over a month
23 32%

How the animals did

Still unwell when reported
15 19%
Died
12 15%
Euthanised
15 19%
Not known
37 47%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
6
8–11 years
23
12+ years
49

About this medicine

Velagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Senvelgo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Velagliflozin cause hyperphosphataemia in cats?
79 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 11 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

All reported side effects of Velagliflozin in cats · Medicines most reported with hyperphosphataemia