Elevated globulins after Velagliflozin (Senvelgo) in cats

The FDA has received 115 reports of elevated globulins in cats after Velagliflozin. That is 2.4% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

115Reports

53%Marked serious

10%Recovered

24%Died or euthanised

10 daysTypical onset

How soon it started

Same day

6 6.5%

1–2 days

17 18%

3–7 days

20 22%

1–4 weeks

17 18%

Over a month

33 35%

How the animals did

Recovered

12 10%

Still unwell when reported

17 15%

Died

7 6.1%

Euthanised

21 18%

Not known

58 50%

Problems reported at the same time

65 57%

61 53%

57 50%

51 44%

50 43%

49 43%

43 37%

40 35%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Velagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Senvelgo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Velagliflozin cause elevated globulins in cats?: 115 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated globulins with similar medicines

Elevated globulins after Bexagliflozin (Bexacat) 74 reports · 1.8% of its reports
Elevated globulins after Insulin 22 reports · 0.6% of its reports

All reported side effects of Velagliflozin in cats · Medicines most reported with elevated globulins