Dehydration after Velagliflozin (Senvelgo) in cats

223 reports to the FDA describe dehydration in cats given Velagliflozin. That is 4.6% of all reports for this medicine, compared with 2.0% across reports for all cat medicines, so it is reported unusually often with this medicine.

223Reports

60%Marked serious

7.6%Recovered

29%Died or euthanised

4 daysTypical onset

How soon it started

Same day

20 10%

1–2 days

54 27%

3–7 days

55 28%

1–4 weeks

31 16%

Over a month

39 20%

How the animals did

Recovered

17 7.6%

Still unwell when reported

42 19%

Died

14 6.3%

Euthanised

50 22%

Not known

100 45%

Problems reported at the same time

130 58%

108 48%

103 46%

89 40%

73 33%

69 31%

67 30%

66 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

110

About this medicine

Velagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Senvelgo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Velagliflozin cause dehydration in cats?: 223 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Bexagliflozin (Bexacat) 243 reports · 6.0% of its reports
Dehydration after Insulin 119 reports · 3.2% of its reports
Dehydration after Methimazole 85 reports · 4.8% of its reports

All reported side effects of Velagliflozin in cats · Medicines most reported with dehydration