Kidney problems after Pyrantel in cats

The FDA has received 34 reports of kidney problems in cats after Pyrantel. That is 6.1% of all reports for this medicine, compared with 4.5% across reports for all cat medicines.

34Reports

71%Marked serious

2.9%Recovered

41%Died or euthanised

4 daysTypical onset

How soon it started

Same day

3 12%

1–2 days

8 32%

3–7 days

4 16%

1–4 weeks

6 24%

Over a month

4 16%

How the animals did

Recovered

1 2.9%

Still unwell when reported

10 29%

Died

7 21%

Euthanised

7 21%

Not known

9 26%

Problems reported at the same time

16 47%

14 41%

13 38%

13 38%

8 24%

Liver problems

8 24%

Hyperphosphataemia

8 24%

Diarrhea

8 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause kidney problems in cats?: 34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Emodepside + Praziquantel (Profender) 88 reports · 1.5% of its reports
Kidney problems after Praziquantel + Pyrantel 21 reports · 1.7% of its reports

All reported side effects of Pyrantel in cats · Medicines most reported with kidney problems