Lethargy after Pyrantel in cats

159 reports to the FDA describe lethargy in cats given Pyrantel. That is 28% of all reports for this medicine, compared with 14% across reports for all cat medicines, so it is reported unusually often with this medicine.

159Reports

36%Marked serious

17%Recovered

23%Died or euthanised

1 daysTypical onset

How soon it started

Same day

38 36%

1–2 days

29 28%

3–7 days

16 15%

1–4 weeks

18 17%

Over a month

4 3.8%

How the animals did

Recovered

26 16%

Recovered with lasting effects

1 0.6%

Still unwell when reported

36 23%

Died

31 19%

Euthanised

6 3.8%

Not known

59 37%

Problems reported at the same time

76 48%

49 31%

38 24%

34 21%

21 13%

17 11%

14 8.8%

14 8.8%

Age of the animals

Under 1 year

123

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause lethargy in cats?: 159 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

Lethargy after Emodepside + Praziquantel (Profender) 909 reports · 16% of its reports
Lethargy after Praziquantel 226 reports · 14% of its reports
Lethargy after Praziquantel + Pyrantel 213 reports · 17% of its reports
Lethargy after Fenbendazole 56 reports · 20% of its reports

All reported side effects of Pyrantel in cats · Medicines most reported with lethargy