Underdose after Praziquantel + Pyrantel in cats

21 reports to the FDA describe underdose in cats given Praziquantel + Pyrantel. That is 1.7% of all reports for this medicine, compared with 0.7% across reports for all cat medicines, so it is reported unusually often with this medicine.

21Reports

52%Marked serious

29%Recovered

0.0%Died or euthanised

Same dayTypical onset

How soon it started

Same day

6 55%

1–2 days

1 9.1%

3–7 days

1 9.1%

1–4 weeks

0 0.0%

Over a month

3 27%

How the animals did

Recovered

6 29%

Not known

15 71%

Problems reported at the same time

Vomiting

9 43%

Incorrect dose administered

6 29%

Seizures

4 19%

Lateral recumbency

4 19%

Itching

4 19%

Diarrhea

3 14%

Didn't stop fleas

3 14%

Inappropriate defecation

2 9.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause underdose in cats?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Underdose with similar medicines

Underdose after Emodepside + Praziquantel (Profender) 54 reports · 0.9% of its reports
Underdose after Praziquantel 73 reports · 4.4% of its reports

All reported side effects of Praziquantel + Pyrantel in cats · Medicines most reported with underdose