Weight loss after Oclacitinib (Apoquel) in cats

31 reports to the FDA describe weight loss in cats given Oclacitinib. That is 6.7% of all reports for this medicine, compared with 4.6% across reports for all cat medicines.

31Reports

61%Marked serious

0.0%Recovered

13%Died or euthanised

9 daysTypical onset

How soon it started

Same day

5 21%

1–2 days

2 8.3%

3–7 days

5 21%

1–4 weeks

2 8.3%

Over a month

10 42%

How the animals did

Still unwell when reported

23 74%

Died

3 9.7%

Euthanised

1 3.2%

Not known

4 13%

Problems reported at the same time

17 55%

8 26%

7 23%

6 19%

6 19%

6 19%

Behaviour change

5 16%

Liver problems

5 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause weight loss in cats?: 31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weight loss with similar medicines

Weight loss after Cyclosporine (Atopica) 394 reports · 13% of its reports

All reported side effects of Oclacitinib in cats · Medicines most reported with weight loss