Vomiting after Oclacitinib (Apoquel) in cats

110 reports to the FDA describe vomiting in cats given Oclacitinib. That is 24% of all reports for this medicine, compared with 18% across reports for all cat medicines.

110Reports

59%Marked serious

19%Recovered

18%Died or euthanised

Same dayTypical onset

How soon it started

Same day

67 67%

1–2 days

17 17%

3–7 days

6 6.0%

1–4 weeks

0 0.0%

Over a month

10 10%

How the animals did

Recovered

21 19%

Still unwell when reported

56 51%

Died

5 4.5%

Euthanised

15 14%

Not known

13 12%

Problems reported at the same time

55 50%

48 44%

47 43%

33 30%

30 27%

28 25%

20 18%

18 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause vomiting in cats?: 110 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

Vomiting after Cyclosporine (Atopica) 929 reports · 31% of its reports

All reported side effects of Oclacitinib in cats · Medicines most reported with vomiting