Didn't work as expected after Itraconazole in cats

The FDA has received 129 reports of didn't work as expected in cats after Itraconazole. That is 30% of all reports for this medicine, compared with 8.7% across reports for all cat medicines, so it is reported unusually often with this medicine.

129Reports
10%Marked serious
2.3%Recovered
1.6%Died or euthanised
37 daysTypical onset
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How soon it started

Same day
2 1.8%
1–2 days
2 1.8%
3–7 days
3 2.6%
1–4 weeks
27 24%
Over a month
80 70%

How the animals did

Recovered
2 1.6%
Recovered with lasting effects
1 0.8%
Still unwell when reported
21 16%
Euthanised
2 1.6%
Not known
103 80%

Problems reported at the same time

9 7.0%
7 5.4%
3 2.3%
Hyperglycaemia
3 2.3%
Neutrophilia
3 2.3%

Age of the animals

Under 1 year
59
1–3 years
22
4–7 years
18
8–11 years
7
12+ years
9

About this medicine

Type: medicine.

Questions owners ask

Can Itraconazole cause didn't work as expected in cats?
129 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 37 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

All reported side effects of Itraconazole in cats · Medicines most reported with didn't work as expected