Didn't work as expected after Methylprednisolone in cats

The FDA has received 227 reports of didn't work as expected in cats after Methylprednisolone. That is 14% of all reports for this medicine, compared with 8.7% across reports for all cat medicines, so it is reported unusually often with this medicine.

227Reports

41%Marked serious

5.3%Recovered

6.2%Died or euthanised

12 daysTypical onset

How soon it started

Same day

20 14%

1–2 days

18 12%

3–7 days

19 13%

1–4 weeks

45 31%

Over a month

44 30%

How the animals did

Recovered

12 5.3%

Still unwell when reported

121 53%

Died

3 1.3%

Euthanised

11 4.8%

Not known

80 35%

Problems reported at the same time

Itching

43 19%

Hair loss

34 15%

Loss of appetite

33 15%

Skin rash or irritation

29 13%

22 9.7%

20 8.8%

17 7.5%

14 6.2%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Methylprednisolone cause didn't work as expected in cats?: 227 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 12 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Ketamine 586 reports · 18% of its reports
Didn't work as expected after Butorphanol 220 reports · 9.8% of its reports
Didn't work as expected after Isoflurane 144 reports · 7.1% of its reports
Didn't work as expected after Tiletamine + Zolazepam 265 reports · 16% of its reports
Didn't work as expected after Propofol 81 reports · 6.9% of its reports
Didn't work as expected after Atipamezole 120 reports · 12% of its reports
Didn't work as expected after Midazolam 31 reports · 4.1% of its reports
Didn't work as expected after Florfenicol + Mometasone + Terbinafine 42 reports · 6.1% of its reports
Didn't work as expected after Orbifloxacin 76 reports · 11% of its reports
Didn't work as expected after Molidustat 194 reports · 32% of its reports

All reported side effects of Methylprednisolone in cats · Medicines most reported with didn't work as expected